Issue date:
Sept. 4-6, 1998
The latest on "unsafe" vitamins
76 million Americans take vitamins. Here's what you can swallow without worry.
espite recent scary media reports based on incomplete
research, vitamin and mineral supplements generally are safe and
beneficial. Still, a few can be toxic at high doses, so be careful.
In my review of cutting-edge research, I have found this to be the best
advice: Don't exceed the doses recommended on supplement labels. If you
take more than one supplement, be sure the amounts of a specific
nutrient do not total a toxic dose. When using vitamins to treat a
particular malady, do so under the supervision of a doctor.
6 TO BE CAUTIOUS ABOUT - Vitamin A. It can accumulate in tissue, causing liver damage at
a long-term daily dose of 25,000 IU. It has been linked to birth defects
at over 10,000 IU daily.
- Vitamin D. It can build up in fat tissues and harm the liver.
In most adults, the toxic dose is over 50,000 IU a day. Children can be
poisoned by as little as 2,000 IU daily.
- Selenium. Too much can harm the liver, nervous system, skin,
nails and teeth. Just 600 micrograms a day might be harmful. Don't take
more than 200mcg daily in a supplement.
- Vitamin B6. Excessive longtime use can cause neurological
problems, such as numb limbs. Symptoms usually disappear after vitamins
are stopped. Many supplements contain B6, so add up your dosages to
avoid a toxic level. Consult a doctor if you use high doses
therapeutically.
- Zinc. Doses over 60 milligrams can interfere with the use of
copper, lowering your antioxidant defenses; damage immunity; and harm
arteries by skewing the ratio of good to bad cholesterol.
- Niacin. Just 10mg of nicotinic acid (but not nicotinamide) can
cause flushing. More than 1,000mg can cause diarrhea, nausea and liver
damage. Most dangerous if improperly used: slow-release nicotinic acid,
sometimes used to improve cholesterol. Take it only under a doctor's
supervision.
4 NOT TO WORRY ABOUT
Regardless of reports you may have heard, top scientists tell me these
important supplements are generally safe: - Vitamin C. Don't credit reports that taking 500-1,000mg
promotes chronic diseases, say U.S. antioxidant authorities.
- Vitamin E. The most common type of vitamin E in supplements,
alpha tocopherol, is, in fact, not dangerous.
- Beta carotene. There's no evidence of danger to non-smokers,
but in smokers, especially those who drink heavily, beta carotene seems
to promote lung cancer.
- Calcium. Contrary to popular belief, calcium and vitamin C may
help retard -- not promote -- kidney stone growth.
HOW SAFE ARE VITAMINS? I believe this chart of supplement risks for adults is the best
information available. It was compiled in 1997
by John Hathcock, Ph.D., after he reviewed hundreds of medical research
reports. Hathcock, formerly with the Food and Drug Administration, now
is with the Council for Responsible Nutrition, a supplement industry
association. The FDA does not issue safety guidelines on dietary supplements. -- Jean Carper | | Nutrient | Daily safe dose1 | Dose at which significant harm is known to occur | | Vitamin A | 10,000 IU | 21,600 IU (liver damage) 10,000 IU (birth defects) | | Beta carotene | 25mg | None known | |
Vitamin D | 800 IU | 2,000 IU | | Vitamin E | 1,200 IU | None known | | Vitamin C | Over 1,000mg | None known | | Thiamin (B1) | 50mg | None known | | Riboflavin (B2) | 200mg | None known | Niacin Nicotinic acid Nicotinamide |
500mg2
1,500mg |
1,000mg2
3,000mg | | Pyridoxine (B6) | 200mg | 500mg | | Folic acid | 1,000mcg | None known | | Vitamin B12 | 3,000mcg | None known | | Calcium | 1,500mg | Over 2,500mg | | Magnesium | 700mg | None known | | Chromium | 1,000mcg | None known | | Iron | 65mg | 100mg | | Selenium | 200mcg | 910mcg | | Zinc
| 30mg | 60mg | 1 No adverse effects have been noted at this level.
2 Half this amount if slow release
Copyright Council for Responsible Nutrition, reprinted by permission
|
SCIENTIFIC SOURCES FOR THIS COLUMN (9/6/98)
John N. Hathcock, Vitamin and Mineral Safety, 61 pages, $10, Council
for Responsible Nutrition, 1300 19th St., N.W., Suite 310, Washington,
D.C. 20036-1609 |